DTC Rx & E-Pharmacy Lifecycle Marketing

Turn First Prescriptions Into Recurring Revenue

Propel builds AI-powered lifecycle campaigns for DTC Rx and e-pharmacy brands, turning first prescriptions into refills and one-time patients into long-term, recurring revenue. We connect your pharmacy and patient data to your ESP, then run HIPAA-aware refill, adherence and winback flows across email and SMS. In DTC Rx, adherence is revenue.

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Scaled the world's leading DTC Rx brands

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Problem

Most DTC Rx Brands Are Losing Patients After the First Fill

You've invested in acquisition. Patients are filling scripts. But the drop-off is brutal:

First-fill patients never refill and you have no automated system to bring them back before they lapse

Refill and adherence reminders are generic or nonexistent, so revenue leaks every cycle

Onboarding flows don't educate patients on dosing, savings or auto-refill, so adherence stays low

Patient data is siloed between your pharmacy system, app and email platform, making compliant personalization impossible

Compliance-sensitive messaging requirements make your team afraid to automate anything

Telemedicine

Solution

Propel builds retention engines for DTC Rx and e-pharmacy brands. We've driven refill adherence, reactivation and subscription revenue for prescription and telepharmacy brands, and we know how to maximize lifecycle revenue while staying compliant.

Customer Success Stories

DTC Rx - Results in Action

From 53% onboarding lifts to 1M+ emails/month — see how we’ve moved the needle for brands like yours.

Try us for 30 days. Love it or get your money back.

Qualified brands can try our services for 30 days. If it doesn’t feel like the right fit get your money back. No fine print, no hassle.

Hear it from our customers

Brilliantly crafted customer experiences

Real results. Real clients. Hear how Propel transformed their customer retention.

Clarissa Bronfman
GTM & Growth Lead, Hook Music
Maya Coben
Director of Marketing, DORSIA
Kaivan Dave
Chief Marketing Officer, Final Round AI
Contact us

Get in touch

Our friendly team is always here to chat.

Here’s what we’ll dig into:

Where your lifecycle flows are underperforming and the revenue you’re missing

How AI-driven personalization can move the needle on retention and LTV

Quick wins your team can action this quarter

Whether Propel is the right fit for your brand, stage, and stack

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Frequently Asked Questions

Everything you need to know about the product and billing. Can’t find the answer you’re looking for? Please chat to our friendly team.

Still have questions?

Our team is here for you.

  • What lifecycle flows do DTC Rx brands need most?

    The highest-ROI flows for DTC Rx are onboarding and dosing education, refill reminders timed to run-out, adherence nudges, auto-refill enrollment, and lapsed-patient winback. We prioritize the ones tied to your refill cycle, then expand.

  • Is your messaging HIPAA compliant for prescription brands?

    Yes, when built correctly: a signed BAA with your platform, protected health information kept out of message content and unsafe fields, and flows triggered off compliant behavioral signals. We configure programs to be compliant by design and work with your compliance team.

  • Can you connect our pharmacy or EHR data to Klaviyo, Customer.io or Braze?

    Yes. Connecting fill, refill and adherence events from your pharmacy or EHR system into your ESP is core to what we do, including keeping patient identity stitched so the right reminder reaches the right person.

  • How quickly can we expect to see results?

    Most DTC Rx brands see measurable lifts within 30 to 60 days. Quick wins like refill reminders and adherence sequences deliver fast, and our 30-day money-back guarantee means you can try us risk-free.

  • What types of pharmacy and Rx brands do you work with?

    We work with telepharmacy, mail-order pharmacy, DTC prescription and chronic-care brands. If refills and adherence drive your revenue, we are a strong fit.

  • Do you replace our in-house team?

    No. We work as an extension of your team, handling lifecycle strategy, campaign execution and data architecture while your team keeps full visibility and approval. Communication happens via Slack, weekly reports and regular check-ins.